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3D CHROMATIN STRUCTURE: De novo genome assemblies of turtles with ZZ/ZW and XX/XY sex chromosomes reveal novel 3D genome folding in amniotes

September 20, 2024

https://www.news.iastate.edu/news/2024/11/11/turtlegenomefolding

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FUNCTIONAL GENOMICS: First turtle organoids developed, with potential for ecological, evolutionary, and biomedical research

February 21, 2023

Preliminary Characterization of Turtle Liver Organoids Provides a Potential Model to Decode Unique Adaptations (submitted to Communications Biology).

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EVO-DEVO: Turtle with ZZ/ZW sex chromosomes retains thermal plasticity during gonadal development

February 8, 2023

Gessler TB, Wu Z, Valenzuela N. 2023. Transcriptomic thermal plasticity underlying gonadal development in a turtle with ZZ/ZW sex chromosomes despite canalized genotypic sex determination.

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SPERMATOGENESIS: Meiotic chromosome dynamics and double strand break formation in turtles and other reptiles

December 12, 2022

Marín-Gual L, González-Rodelas L, Garcias MM, Kratochvil L, Valenzuela N, Georges A, Waters PD, Ruiz-Herrera A. 2022.

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TRANSPOSABLE ELEMENTS mediate sex chromosome evolution and dosage compensation in ZZ/ZW but not XX/XY turtles

August 3, 2022

Montiel EE, Badenhorst D, Lee LS, Valenzuela N. 2022.

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ECOTOXICOLOGY: Cadmium affects DNA methylation and transcription in painted turtle embryos

August 3, 2022

Mizoguchi1 B, Topping NE, Lavin AM and Valenzuela N. 2022. Cadmium ecotoxic effects on embryonic Dmrt1 and aromatase expression in Chrysemys picta turtles may

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SEX DETERMINATION: highest pivotal temperature in Podocnemis sextuberculata turtles

August 3, 2022

Camillo CS, Valenzuela N, Johnson SA. 2022.

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Dr. Valenzuela elected as AAAS Fellow

January 26, 2022

Dr.

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Edited Themed Issue on Sexual Development and the Environment

September 24, 2021

Sexual Development and the Environment

Special Topic Issue of: Sexual Development 2021, Vol. 15, No. 1-3

Editor(s): Valenzuela , Nicole (Ames, IA)
Schartl, Manfred (Wuerzburg)

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DOSAGE COMPENSATION & EVODEVO: Thermosensitive sex chromosome dosage compensation in ZZ/ZW softshell turtles, Apalone spinifera.

January 8, 2021

Bista B, Wu Z, Literman R, and Valenzuela N.

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EVOLUTION: Podocnemis expansa turtles hint to a unifying explanation for the evolution of temperature dependent sex determination in long-lived and short-lived vertebrates

January 7, 2021

Valenzuela N.

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NATURE PAPER: The tuatara genome reveals ancient features of amniote evolution

August 6, 2020

Nature. OPEN ACCESS: Gemmell, N.J., Rutherford, K., Prost, S., Tollis, M., Winter, D., Macey, J.R., Adelson, D.L., Suh, A., Bertozzi, T., Grau, J.H., Organ, C., Gardner, P.P., Muffato, M., Patricio, M., Billis,

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PHYLOGENOMICS: Karyotypic evolution of sauropsid vertebrates illuminated by optical and physical mapping of the painted turtle and slider turtle genomes

July 31, 2020

Lee LS, Navarro-Domínguez BM, Wu Z, Montiel EE, Badenhorst D, Bista B, Gessler TB, and Valenzuela N. 2020. Karyotypic evolution of sauropsid vertebrates illuminated by optical and physical mapping of the

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TURTLE SEX CHROMOSOME EVOLUTION: Turtle insights into the evolution of the reptilian karyotype and the genomic architecture of sex determination

July 5, 2020

Bista B. and Valenzuela N. 2020. Turtle insights into the evolution of the reptilian karyotype and the genomic architecture of sex determination. Genes 11 (4): 416.

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EVODEVO: Alternative splicing and thermosensitive expression of Dmrt1 during urogenital development in the painted turtle, Chrysemys picta.

January 27, 2020

Mizoguchi B.A. and Valenzuela N. 2020. Alternative splicing and thermosensitive expression of Dmrt1 during urogenital development in the painted turtle, Chrysemys picta.

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PHYLOGENOMICS: Emydura subglobosa sex chromosome paper selected as EDITOR'S CHOICE (free download)

August 26, 2019

Cytogenetic and Genome Research 2019 PDF

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CONSERVATION: Extreme thermal fluctuations from climate change unexpectedly accelerate demographic collapse of vertebrates with temperature dependent sex determination.

March 15, 2019

Scientific Reports 2019 PDF

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PHYLOGENOMICS: Chromosomal rearrangements during turtle evolution altered the synteny of genes involved in vertebrate sex determination.

January 29, 2019

Cytogenetic and Genome Research 2019 PDF

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MOLECULAR EVOLUTION: Putative independent evolutionary reversals from genotypic to temperature-dependent sex determination are associated with accelerated evolution of sex-determining genes in turtles.

January 17, 2019

Journal of Molecular Evolution. 2018. PDF

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EPIGENETICS: Thermal response of epigenetic genes informs turtle sex determination with and without sex chromosomes

October 4, 2018

Sexual Development 2018. PDF

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